Form 4 for IONS IONIS PHARMACEUTICALS INC
Accepted 2025-10-16 00:00:00 ET · period of report 2025-10-15 · accession 0000874015-25-000260 · SEC index · Original document
Summary rows
Aggregated the way they appear in lists: one row per insider, transaction code and security table.
| X | Filed | Traded | Ticker | Insider | Title | Type | Price | Qty | Owned | ΔOwn | Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DM | 2025-10-16 | 2025-10-15 | IONS | Devers Shannon L. | EVP, Chief Human Resources Ofc | M - OptEx | $33.00 | +8,820 | 21.9K | +67% | +$291.1K |
| DM | 2025-10-16 | 2025-10-15+ | IONS | Devers Shannon L. | EVP, Chief Human Resources Ofc | S - Sale+OE | $73.06 | -7,263 | 17.5K | -29% | -$530.6K |
| DM | 2025-10-16 | 2025-10-15 | IONS | Devers Shannon L. | EVP, Chief Human Resources Ofc | M - OptEx | $0.00 | -8,820 | 60.4K | -13% | $0 |
Purchase Sale Sale after option exercise All abbreviations
Every reported transaction
| # | Table | Security | Date | Code | A/D | Shares | Price | Owned after | Own | Exercise / expiry | Underlying | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Common | Common Stock | 2025-10-15 | M | A | 2,820 | $0.00 | 18,757 | D | — | — | (F3) Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award. |
| 2 | Common | Common Stock | 2025-10-15 | S | D | 6,000 | $72.94 | 15,937 | D | — | — | (F1) Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 3, 2024. (F2) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $72.775 to $73.04 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4. |
| 3 | Common | Common Stock | 2025-10-15 | M | A | 6,000 | $48.51 | 21,937 | D | — | — | |
| 4 | Common | Common Stock | 2025-10-16 | S | D | 1,263 | $73.62 | 17,494 | D | — | — | (F4) The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice. |
| 5 | Derivative | Non-Qualified Stock Option (right to buy) | 2025-10-15 | M | D | 6,000 | $0.00 | 0 | D | $48.51 · 2021-04-05 to 2027-04-04 | 6,000 Common Stock | |
| 6 | Derivative | Restricted Stock Unit | 2025-10-15 | M | D | 2,820 | $0.00 | 60,406 | D | $0.00 · 2025-10-15 to — | 2,820 Common Stock | (F5) Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value. (F6) Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company. |