InsiderTrades

Form 4 for IONS IONIS PHARMACEUTICALS INC

Accepted 2025-10-16 00:00:00 ET · period of report 2025-10-15 · accession 0000874015-25-000262 · SEC index · Original document

Summary rows

Aggregated the way they appear in lists: one row per insider, transaction code and security table.

X Filed Traded Ticker Insider Title Type Price Qty Owned ΔOwn Value
DI 2025-10-16 2025-10-15 IONS Swayze Eric EVP Research M - OptEx $0.00 +125 309 +68% $0
DI 2025-10-16 2025-10-16 IONS Swayze Eric EVP Research S - Sale+OE $73.62 -53 256 -17% -$3,902
DI 2025-10-16 2025-10-15 IONS Swayze Eric EVP Research M - OptEx $0.00 -125 497 -20% $0

Purchase Sale Sale after option exercise All abbreviations

Every reported transaction

#TableSecurityDateCodeA/DSharesPriceOwned afterOwnExercise / expiryUnderlyingFootnotes
1 Common Common Stock 2025-10-15 M A 125 $0.00 309 I by Son — — (F1) Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.
2 Common Common Stock 2025-10-16 S D 53 $73.62 256 I by Son — — (F2) The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice.
3 Derivative Restricted Stock Unit 2025-10-15 M D 125 $0.00 497 I by Son $0.00 · 2025-10-15 to — 125 Common Stock (F3) Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value. (F4) Restricted Stock Units vest in four equal annual installments. Upon vesting, the restricted stock units will be paid out in whole shares of Ionis common stock or cash as may be determined by the Company.