Form 4 for IONS IONIS PHARMACEUTICALS INC
Accepted 2025-11-28 00:00:00 ET · period of report 2025-11-25 · accession 0000874015-25-000286 · SEC index · Original document
Summary rows
Aggregated the way they appear in lists: one row per insider, transaction code and security table.
| X | Filed | Traded | Ticker | Insider | Title | Type | Price | Qty | Owned | ΔOwn | Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DMI | 2025-11-28 | 2025-11-25 | IONS | KLEIN JOSEPH III | Dir | S - Sale+OE | $80.00 | -12.0K | 0 | -100% | -$960.0K |
| DMI | 2025-11-28 | 2025-11-25 | IONS | KLEIN JOSEPH III | Dir | M - OptEx | $0.00 | +12.0K | 4,000 | New | $0 |
| DMI | 2025-11-28 | 2025-11-25 | IONS | KLEIN JOSEPH III | Dir | M - OptEx | $0.00 | -12.0K | 8,000 | -60% | $0 |
Purchase Sale Sale after option exercise All abbreviations
Every reported transaction
| # | Table | Security | Date | Code | A/D | Shares | Price | Owned after | Own | Exercise / expiry | Underlying | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Common | Common Stock | 2025-11-25 | S | D | 4,000 | $80.00 | 0 | I by Trust | — | — | (F1) Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 3, 2024 (F2) The reporting person disclaims beneficial ownership of all securities held in the children's trusts, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. |
| 2 | Common | Common Stock | 2025-11-25 | M | A | 4,000 | $0.00 | 4,000 | I by Trust | — | — | |
| 3 | Common | Common Stock | 2025-11-25 | S | D | 4,000 | $80.00 | 0 | I by Trust | — | — | (F1) Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 3, 2024 (F2) The reporting person disclaims beneficial ownership of all securities held in the children's trusts, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. |
| 4 | Common | Common Stock | 2025-11-25 | M | A | 4,000 | $0.00 | 4,000 | I by Trust | — | — | |
| 5 | Common | Common Stock | 2025-11-25 | S | D | 4,000 | $80.00 | 0 | I by Trust | — | — | (F1) Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on January 3, 2024 (F2) The reporting person disclaims beneficial ownership of all securities held in the children's trusts, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. |
| 6 | Common | Common Stock | 2025-11-25 | M | A | 4,000 | $0.00 | 4,000 | I by Trust | — | — | |
| 7 | Derivative | Non-Qualified Stock Option (right to buy) | 2025-11-25 | M | D | 4,000 | $0.00 | 4,000 | I by Trust | $60.20 · 2021-07-01 to 2030-06-30 | 4,000 Common Stock | |
| 8 | Derivative | Non-Qualified Stock Option (right to buy) | 2025-11-25 | M | D | 4,000 | $0.00 | 0 | I by Trust | $60.20 · 2021-07-01 to 2030-06-30 | 4,000 Common Stock | |
| 9 | Derivative | Non-Qualified Stock Option (right to buy) | 2025-11-25 | M | D | 4,000 | $0.00 | 8,000 | I by Trust | $60.20 · 2021-07-01 to 2030-06-30 | 4,000 Common Stock |