InsiderTrades

Form 4 for IONS IONIS PHARMACEUTICALS INC

Accepted 2026-06-03 17:34:36 ET · period of report 2026-06-01 · accession 0000874015-26-000188 · SEC index · Original document

Summary rows

Aggregated the way they appear in lists: one row per insider, transaction code and security table.

X Filed Traded Ticker Insider Title Type Price Qty Owned ΔOwn Value
DT 2026-06-03 17:34 2026-06-01 IONS BERTHELSEN SPENCER R Dir M - OptEx $24.42 +8,000 164.0K +5% +$195.4K
DT 2026-06-03 17:34 2026-06-01 IONS BERTHELSEN SPENCER R Dir S - Sale+OE $75.67 -8,000 156.0K -5% -$605.4K
DT 2026-06-03 17:34 2026-06-01 IONS BERTHELSEN SPENCER R Dir M - OptEx $0.00 -8,000 8,000 -50% $0

Purchase Sale Sale after option exercise All abbreviations

Every reported transaction

#TableSecurityDateCodeA/DSharesPriceOwned afterOwnExercise / expiryUnderlyingFootnotes
1 Common Common Stock 2026-06-01 M A 8,000 $24.42 164,013 D — —
2 Common Common Stock 2026-06-01 S D 8,000 $75.67 156,013 D — — (F1) Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 12, 2025.
3 Derivative Non-Qualified Stock Option (right to buy) 2026-06-01 M D 8,000 $0.00 8,000 D $24.42 · 2017-07-01 to 2026-06-30 8,000 Common Stock