InsiderTrades

Form 4 for VRTX Vertex Pharmaceuticals

Accepted 2025-11-17 00:00:00 ET · period of report 2025-11-13 · accession 0000875320-25-000234 · SEC index · Original document

Summary rows

Aggregated the way they appear in lists: one row per insider, transaction code and security table.

X Filed Traded Ticker Insider Title Type Price Qty Owned ΔOwn Value
DM 2025-11-17 2025-11-13+ VRTX LEIDEN JEFFREY M Executive COB, Dir M - OptEx $88.59 +73.3K 37.9K New +$6.49M
DM 2025-11-17 2025-11-13+ VRTX LEIDEN JEFFREY M Executive COB, Dir S - Sale+OE $440.60 -73.3K 24.1K -75% -$32.29M
DM 2025-11-17 2025-11-13+ VRTX LEIDEN JEFFREY M Executive COB, Dir M - OptEx $0.00 -73.3K 13.8K -84% $0

Purchase Sale Sale after option exercise All abbreviations

Every reported transaction

#TableSecurityDateCodeA/DSharesPriceOwned afterOwnExercise / expiryUnderlyingFootnotes
1 Common Common Stock 2025-11-13 M A 19,688 $91.05 43,714 D — —
2 Common Common Stock 2025-11-13 S D 18,528 $440.22 25,186 D — — (F2) Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price. (F3) Open market sales reported on this line occurred at a weighted average price of $440.22 (range $440.00 to $440.99).
3 Common Common Stock 2025-11-13 S D 1,160 $441.05 24,026 D — — (F2) Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price. (F4) Open market sales reported on this line occurred at a weighted average price of $441.05 (range $441.00 to $441.10).
4 Common Common Stock 2025-11-14 S D 40 $442.00 24,026 D — —
5 Common Common Stock 2025-11-14 M A 39,769 $86.52 77,630 D — —
6 Common Common Stock 2025-11-14 S D 32,234 $440.30 45,396 D — — (F2) Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price. (F5) Open market sales reported on this line occurred at a weighted average price of $440.30 (range $440.00 to $440.99).
7 Common Common Stock 2025-11-14 S D 21,330 $441.35 24,066 D — — (F2) Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price. (F6) Open market sales reported on this line occurred at a weighted average price of $441.35 (range $441.00 to $441.99).
8 Common Common Stock 2025-11-14 M A 13,835 $91.05 37,861 D — —
9 Derivative Stock Option (Right to Buy) 2025-11-14 M D 39,769 $0.00 63,781 D $86.52 · — to 2027-02-02 39,769 Common Stock (F7) Fully vested.
10 Derivative Stock Option (Right to Buy) 2025-11-14 M D 13,835 $0.00 1 D $91.05 · — to 2026-02-01 13,835 Common Stock (F7) Fully vested.
11 Derivative Stock Option (Right to Buy) 2025-11-13 M D 19,688 $0.00 13,836 D $91.05 · — to 2026-02-01 19,688 Common Stock (F7) Fully vested.