InsiderTrades

Form 4 for ZYME Zymeworks Inc.

Accepted 2025-06-27 00:00:00 ET · period of report 2025-06-26 · accession 0000935836-25-000438 · SEC index · Original document

Summary rows

Aggregated the way they appear in lists: one row per insider, transaction code and security table.

X Filed Traded Ticker Insider Title Type Price Qty Owned ΔOwn Value
DI 2025-06-27 2025-06-26 ZYME NODELMAN OLEG Dir, 10% X - OptEx $0.00 +5.09M 22.97M +28% $0
DI 2025-06-27 2025-06-26 ZYME NODELMAN OLEG Dir, 10% F - Tax $12.71 -41 22.97M -0.0% -$521.11
DI 2025-06-27 2025-06-26 ZYME NODELMAN OLEG Dir, 10% X - OptEx $0.00 -5.09M 0 -100% $0

Purchase Sale Sale after option exercise All abbreviations

Every reported transaction

#TableSecurityDateCodeA/DSharesPriceOwned afterOwnExercise / expiryUnderlyingFootnotes
1 Common Common Stock 2025-06-26 X A 5,086,480 $0.00 22,970,388 I See Note — — (F2) Qualified Fund acquired 4,818,424 shares of Common Stock in connection with the exercise of the pre-funded warrants. (F3) After the transactions reported herein, Qualified Fund held 21,582,563 shares of the Issuer's Common Stock. (F1) The reporting persons are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.
2 Common Common Stock 2025-06-26 F D 41 $12.71 22,970,388 I See Note — — (F3) After the transactions reported herein, Qualified Fund held 21,582,563 shares of the Issuer's Common Stock. (F1) The reporting persons are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.
3 Derivative Pre-Funded Warrants (right to acquire) 2025-06-26 X D 5,086,521 $0.00 0 I See note $0.00 · 2023-12-26 to — 5,086,521 Common Stock (F5) Qualified Fund exercised 4,818,462 of the pre-funded warrants reported in this transaction. (F1) The reporting persons are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein. (F6) The pre-funded warrants did not have an expiration date.