InsiderTrades

Form 4 for RYTM RHYTHM PHARMACEUTICALS, INC.

Accepted 2025-11-12 00:00:00 ET · period of report 2025-11-07 · accession 0001104659-25-110430 · SEC index · Original document

Summary rows

Aggregated the way they appear in lists: one row per insider, transaction code and security table.

X Filed Traded Ticker Insider Title Type Price Qty Owned ΔOwn Value
DM 2025-11-12 2025-11-07+ RYTM Cramer Pamela J. CHRO S - Sale+OE $99.00 -22.9K 20.8K -52% -$2.26M
DM 2025-11-12 2025-11-07+ RYTM Cramer Pamela J. CHRO M - OptEx $11.51 +22.9K 29.6K +339% +$263.1K
DM 2025-11-12 2025-11-07+ RYTM Cramer Pamela J. CHRO M - OptEx $0.00 -22.9K 7,035 -76% $0

Purchase Sale Sale after option exercise All abbreviations

Every reported transaction

#TableSecurityDateCodeA/DSharesPriceOwned afterOwnExercise / expiryUnderlyingFootnotes
1 Common Common Stock 2025-11-10 S D 3,515 $100.00 20,814 D — —
2 Common Common Stock 2025-11-10 M A 3,515 $6.80 24,329 D — —
3 Common Common Stock 2025-11-07 M A 10,546 $6.80 40,165 D — —
4 Common Common Stock 2025-11-07 S D 19,351 $98.82 20,814 D — —
5 Common Common Stock 2025-11-07 M A 8,805 $19.02 29,619 D — —
6 Derivative Stock Options (Right to Buy) 2025-11-10 M D 3,515 $0.00 3,520 D $6.80 · — to 2032-02-08 3,515 Common Stock (F3) The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.
7 Derivative Stock Options (Right to Buy) 2025-11-07 M D 8,805 $0.00 5,257 D $19.02 · — to 2031-07-25 8,805 Common Stock (F2) The stock option is fully vested.
8 Derivative Stock Options (Right to Buy) 2025-11-07 M D 10,546 $0.00 7,035 D $6.80 · — to 2032-02-08 10,546 Common Stock (F3) The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.