Form 4 for PRAX Praxis Precision Medicines, Inc.
Accepted 2025-11-21 00:00:00 ET · period of report 2025-11-20 · accession 0001104659-25-115098 · SEC index · Original document
Summary rows
Aggregated the way they appear in lists: one row per insider, transaction code and security table.
| X | Filed | Traded | Ticker | Insider | Title | Type | Price | Qty | Owned | ΔOwn | Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DM | 2025-11-21 | 2025-11-20 | PRAX | Mastrocola Lauren | Principal Accounting Off | S - Sale+OE | $192.08 | -13.6K | 12.6K | -52% | -$2.61M |
| DM | 2025-11-21 | 2025-11-20 | PRAX | Mastrocola Lauren | Principal Accounting Off | M - OptEx | $61.12 | +13.6K | 12.0K | New | +$831.3K |
| DM | 2025-11-21 | 2025-11-20 | PRAX | Mastrocola Lauren | Principal Accounting Off | M - OptEx | $0.00 | -13.6K | 11.4K | -54% | $0 |
Purchase Sale Sale after option exercise All abbreviations
Every reported transaction
| # | Table | Security | Date | Code | A/D | Shares | Price | Owned after | Own | Exercise / expiry | Underlying | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Common | Common Stock | 2025-11-20 | S | D | 2,145 | $192.71 | 10,441.66 | D | — | — | (F2) The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $192.552 to $193.109. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote. |
| 2 | Common | Common Stock | 2025-11-20 | S | D | 11,455 | $191.96 | 12,586.66 | D | — | — | (F1) The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $191.500 to $192.432. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote. |
| 3 | Common | Common Stock | 2025-11-20 | M | A | 5,250 | $56.94 | 24,041.66 | D | — | — | |
| 4 | Common | Common Stock | 2025-11-20 | M | A | 2,351 | $44.40 | 18,791.66 | D | — | — | |
| 5 | Common | Common Stock | 2025-11-20 | M | A | 1,047 | $49.50 | 11,488.66 | D | — | — | |
| 6 | Common | Common Stock | 2025-11-20 | M | A | 207 | $44.40 | 16,440.66 | D | — | — | |
| 7 | Common | Common Stock | 2025-11-20 | M | A | 2,680 | $43.37 | 16,233.66 | D | — | — | |
| 8 | Common | Common Stock | 2025-11-20 | M | A | 1,557 | $133.65 | 13,553.66 | D | — | — | |
| 9 | Common | Common Stock | 2025-11-20 | M | A | 508 | $83.85 | 11,996.66 | D | — | — | |
| 10 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 2,351 | $0.00 | 981 | D | $44.40 · — to 2033-01-12 | 2,351 Common Stock | (F7) The shares underlying this stock option vested as to 25% on January 12, 2024 and the remaining shares vest in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date. |
| 11 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 207 | $0.00 | 0 | D | $44.40 · 2023-01-12 to 2033-01-12 | 207 Common Stock | |
| 12 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 2,680 | $0.00 | 9,320 | D | $43.37 · — to 2034-01-12 | 2,680 Common Stock | (F6) The shares underlying this stock option vested as to 50% on January 12, 2024 and the remaining 50% vesting over a four-year period, with 25% of such shares vesting on January 12, 2025 and the remaining vesting in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date. |
| 13 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 1,557 | $0.00 | 0 | D | $133.65 · — to 2030-09-13 | 1,557 Common Stock | (F5) This option was fully vested as of September 8, 2024. |
| 14 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 508 | $0.00 | 0 | D | $83.85 · — to 2030-06-04 | 508 Common Stock | (F4) This option was fully vested as of May 28, 2024. |
| 15 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 1,047 | $0.00 | 0 | D | $49.50 · — to 2029-09-23 | 1,047 Common Stock | (F3) This option was fully vested as of January 1, 2023. |
| 16 | Derivative | Stock Option (Right to Buy) | 2025-11-20 | M | D | 5,250 | $0.00 | 11,376 | D | $56.94 · — to 2034-07-29 | 5,250 Common Stock | (F8) The shares underlying this stock option vested as to 7/48ths on July 29, 2024 and the remaining shares vest in substantially equal monthly installments over the following 41 months, subject to the Reporting Person's continued service through each vesting date. |